DANGEROUS UNIVERSAL DONORS

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چکیده

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منابع مشابه

Prevalence and Haemolytic Significance of Red Cell Antibodies among Dangerous Universal Donors in a Tertiary Care Hospital in South India

Background and Aims: A subgroup of group O individuals called ‘dangerous universal donors’ have immune (IgG) anti A and anti B antibodies which are active at 37˚C and capable of reacting with the red cells and causing lysis. The aim of this study was to find the prevalence of dangerous O group among the voluntary donor population and to assess the relation between the degree of haemolysis and t...

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Different Immune Responses in Dangerous O Blood Donors

Background & Objective: Dangerous O is very important to transfusion medicine and there has been reports by Food and Drug Administration (FDA) regarding some death relating incidences. As high iso-antibody production is closely associated with different immune reactions, a survey on the different immune response of dangerous O donors can lead to understanding their immune respo...

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Dangerous universal donors: the reality of the Hemocentro in Belo Horizonte, Minas Gerais

BACKGROUND The term dangerous universal blood donor refers to potential agglutination of the erythrocytes of non-O recipients due to plasma of an O blood group donor, which contains high titers of anti-A and/or anti-B hemagglutinins. Thus, prior titration of anti-A and anti-B hemagglutinins is recommended to prevent transfusion reactions. OBJECTIVE The aim of this study was to estimate the fr...

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Dangerous universal donors; II. Further observations on in vivo and in vitro behavior of isoantibodies of immune type present in group O blood.

By DONALD M. ERvIN, M.D., RICHARD M. CHRISTIAN, M.D., AND LAWRENCE E. YOUNG, M.D. H EMOLYTIC reactions resulting from transfusion of group 0 plasma into group A recipients, while not common, have been reported with increasing frequency during the past few years.’5 Reactions of this type are usually not as dramatic or as severe as those resulting from transfusion of incompatible whole blood and ...

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Donors, donors, and more donors.

The safety of healthy peripheral blood stem cell (PBSC) donors receiving recombinant human granulocyte colony-stimulating factor (rhG-CSF) is a topic that has received considerable attention in recent literature.1-3 The short-term adverse events related to both mobilization and collection as well as the problem of long-term safety monitoring have been discussed extensively, although the latter ...

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ژورنال

عنوان ژورنال: Blood

سال: 1950

ISSN: 0006-4971,1528-0020

DOI: 10.1182/blood.v5.6.553.553